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MammoSite© Breast Cancer Radiation Dramatically Reduces Duration of Treatment
Robotic Treatment Planning Technology Improves Treatment of Breast, Head and Neck Cancer
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"Made For Me" Boutique
Clinical Trials
Trinitas Comprehensive Cancer Center Unveils New Jersey's First Trilogy Linear Accelerator
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The Trinitas Comprehensive Cancer Center is located at our Williamson St. Campus.

Please call 908-994-8000, or use these links for Maps and Directions.

 

MAMMOSITE© BREAST CANCER RADIATION DRAMATICALLY REDUCES DURATION OF TREATMENT
5-day treatment offers "gift of time"

Women with early stage breast cancer can now benefit from an innovative radiation therapy treatment which can be completed in less than 20 percent of the time required for traditional treatments.

The new treatment option offered at Trinitas Comprehensive Cancer Center, called MammoSite© therapy, is usually completed in five days and is considered the treatment of choice for thousands of women who would otherwise require up to six weeks of daily radiation therapy. "Often," reports Linda Veldkamp, Chief Physicist and Director of Radiation Oncology, "patients say their lives are too busy and don't have a lot of time for their treatment. Now, we can offer many women an effective breast-sparing treatment option that can be delivered in the shortest amount of time. MammoSite therapy gives women the gift of time and lets them get back to their daily lives."

The traditional course of radiation therapy following a lumpectomy is delivered over six or more weeks on a daily basis to ensure that the tumor does not recur. Now, however, the innovative MammoSite treatment can reduce the time required for post-operative radiation therapy from six weeks to as little as 5 days.

Today, more and more women with early stage breast cancer are choosing to effectively treat their tumor and preserve their breast through an option known as Breast Conservation Therapy (BCT). Yet only 60% of women who are eligible for BCT receive it instead of an invasive mastectomy. The expectation is that with the MammoSite treatment option even more women will choose BCT.

The MammoSite procedure starts with a breast sparing surgical removal of the cancerous tumor via a lumpectomy. "During or shortly after lumpectomy surgery, the patient undergoes a minimally invasive procedure wherein a MammoSite, a small balloon attached to a thin catheter, is gently inserted into the lumpectomy cavity -- the space left inside the breast after the tumor is removed," explained Dr. James Frost, a surgeon at Trinitas Hospital. "The balloon end of the catheter is inflated with saline solution so that the surrounding tissue conforms to the shape of the balloon," said Dr. Ronald D. Pallant, the first surgeon at Trinitas to perform the Mammosite procedure. The surgical site is then dressed and the patient is sent home to recover.

During subsequent out-patient radiation therapy sessions, (usually twice a day for five days), a "seed" smaller than a grain of rice is inserted through the catheter into the MammoSite apparatus. There, the seed remains for just a few minutes where it delivers a customized and targeted dose of radiation to the lumpectomy site and then is removed. Because the radioactive seed is inside the balloon, focused radiation is delivered only to that internal area of the breast where the cancer is most likely to recur. From a safety perspective, Veldkamp, points out that "some tumors are very close to the chest wall and MammoSite's confined and targeted treatment minimizes the radiation exposure to vital organs such as the heart and lungs while directing it right around the tumor area."

MammoSite is the mostly widely-used therapy in a category called partial breast irradiation (PBI). MammoSite has been used to treat more than 17,000 breast cancer patients. The first four-year data presented at the American Society for Therapeutic Radiology and Oncology meeting in October 2005 demonstrated that no patients experienced recurrence after treatment with MammoSite. A five-year follow-up study published in the Journal of the National Cancer Institute found that PBI using a similar technique to MammoSite RTS produces comparable results to conventional whole breast radiation therapy in preventing breast cancer recurrence in appropriately selected women treated with BCT.

Mammosite is an outpatient therapy that minimizes the effect of radiation to healthy tissue and reduces the potential for side effects. The procedure offers good to excellent cosmetic results for most women and no radiation remains in the woman's body between treatments or after the final treatment is over.

 

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